2024-2025 Academic Catalog 
    
    Dec 03, 2024  
2024-2025 Academic Catalog

BCMB 275 - Protein Chemistry


An in-depth discussion on protein structure and function. Techniques routinely used to determine protein structure, function, and the underlying principles of enzyme catalysis will be examined.  Topics include protein structure hierarchy, physicochemical properties that govern protein folding, enzyme cofactors, protein synthesis and degradation, recombinant protein expression systems, protein purification methods, enzyme assays and protein quantification, posttranslational modifications, isotopic and fluorescent protein labeling strategies, mass spectrometry with proteins and peptides, protein-protein/DNA/RNA interactions, X-ray crystallography, 2D and 3D NMR spectroscopy with proteins, and protein structure visualization.

Prerequisites: BCMB 271  or permission of instructor.

Anticipated Terms Offered: Offered every other year